Mephedrone: Evaluation of Extraction using Mixed Mode Cation Exchange SPE with UPLC-MS/MS Analysis
Part No: PN38
Issued year: 2011
File size: 0.17mb
File type: pdf
Mephedrone (MCAT) is a ‘designer drug’ synthesised to mimic the amphetamine class of compounds. Due to its perceived ‘ecstasy like’ effects of euphoria, excitement and alertness combined with ease of availability, this (until recently) unregulated drug (legal high) has found widespread abuse in the UK in recent years. Harmful effects associated with mephedrone are still being studied but after several deaths were linked to the abuse of the drug, the UK Government made this a Class B substance. Mephedrone extraction was evaluated on three mixed mode cation exchange SPE sorbents: EVOLUTE® CX, EVOLUTE® WCX and ISOLUTE® HCX.
DOA, ISOLUTE, EVOLUTE, Amphetamine
Application Notes
Column
Forensic
LC-MS/MS
Mephedrone
Plasma
Urine
Whole blood